BRAIN - Metastatic melanoma

The cortex and the white matter showed numerous black spots, up to 3.0 mm. in diameter.
At the age of 58, this man had a left upper lobectomy for a lesion seen on X-ray. This was shown to be a metastatic melanoma; a melanoma had been removed from his back three years before. Postoperatively, he was noted to have two rapidly-growing nodules in the scalp and one on his back. At autopsy, metastatic melanoma was demonstrated in liver, adrenal gland, kidney, heart and brain.