BRAIN - Meningoencephalitis and cerebral oedema

Specimen consists of a slice of brain sectioned in the coronal plane. The most striking feature is the pronounced cerebral oedema which has almost totally obliterated the lateral ventricle. The meninges appear slightly cloudy and there is a mild degree of vascular congestion.
The patient was admitted with a short history of headache and confusion. Lumbar puncture was performed and this suggested meningitis. A subsequent EEG was consistent with encephalitis. Histologic examination of the meninges showed a variable infiltrate of lymphocytes and macrophages. The infiltrate was most pronounced over the temporal lobe. There were also perivascular collections of lymphocytes within the white and grey matter. The findings were those of a meningoencephalitis which was probably of a viral aetiology.