BRAIN - Astrocytoma

The specimen is a brain sectioned in the horizontal plane. There is diffuse swelling of the brain with flattening of the gyri. The left temporal lobe is enlarged by a haemorrhagic tumour mass. This contains focal areas of necrosis and cystic degeneration. The anterior part of the tumour lies in the frontal operculum, while medially there is infiltration of the insula and claustrum. The adjacent brain shows marked oedema with distortion of the ventricular system and pronounced midline shift to the right. Examination of the inferior surface of the brain shows cerebellar grooving consistent with raised intracranial pressure. Histologic examination of the tumour showed an astrocytoma grade IV.