BONE - Sarcoma

The specimen, amputated in the lower thigh, shows the lower end of the femur, the patella and the upper end of the tibia. The tibia is expanded, and its structure replaced by tumour, which is extending through the cortex posteriorly into the muscle mass. As far as can be seen, the joint is not involved.
This patient died 11 months after amputation; the cause of death was intestinal obstruction secondary to an ileo-ileal intussusception at the apex of which was a pedunculated sub-mucosal secondary sarcomatous deposit. There were other secondary deposits in the lungs, liver, kidney and lymph nodes in the neck. Histologically, the tumour is described as a spindle-celled sarcoma, some areas of which show the structure of an apparently benign giant cell tumour.