SKULL - Paget's disease

The specimen is part of the vault of the skull which is grossly thickened, measuring up to 5 cm in depth. The distinction between the inner and outer tables is not clear and in some areas there is a haemorrhagic appearance consistent with an increased vascularity of the bone.
The specimen comes from the skull of a 75-year-old woman who was found lying face downwards, dead, in the bathroom. At autopsy, much of the skull was involved by Paget's disease, as was the left tibia, and death was ascribed to heart failure secondary to the greatly increased vascularity of the skull and tibia.