The specimen is a hemisected proximal half of tibia with attached fibula. Situated on the upper
lateral portion of the tibia there is invasive tumour, this appears to originate in the metaphysis and
extends towards the diaphysis. The tumour is pale with extensive areas of necrosis and
haemorrhage. There is also an extra-osseous portion of the tumour extending through the
periostium. Histological examination of the tumour showed it to be an osteogenic sarcoma
consisting predominantly of osteoblast-like cells.
The patient was a 20-year-old male who presented with a three months history of pain in
the left knee. This was most pronounced at night. On examination it was noted that the lateral
portion of the tibia was enlarged and tender. There was a full range of movement, however pain
was noted on flexion of the knee joint. The patient underwent an above knee amputation, but
developed pulmonary metastases within six months of diagnosis.