COLON - Ulcerative colitis

The specimen is a length of colon, opened to show extensive polypoidal changes in the mucosa. The polyps are single in some areas, multiple and many-branched in others; it is possible to visualise their origin from surviving mucosa as the ulcerative colitis became quiescent. The bowel wall shows little thickening. There is some thickening of the serosa, although this is not marked. With this degree of mucosal proliferation, the chances of malignant change are enhanced.