COLON - Ulcerative colitis

This specimen consists of caecum, ascending and transverse colon. There is a small area of apparently normal mucosa at the distal end. Elsewhere the mucosa is thrown into a cobblestone pattern and shows numerous polypoid projections particularly in the ascending colon.
This woman was admitted to hospital first in 1975 at the age of 38 following a twelve-month history of frequent bloody bowel motions as well as vomiting and weight loss. In the intervening time, she suffered exacerbations of disease and was finally admitted for resection. Histology of the lesion was that of active chronic ulcerative colitis.