LIVER - Secondary leiomyosarcoma

The specimen is part of an enlarged liver (total weight of the organ 3100 grams), showing a large tumour in the right lobe. The tumour shows a large area of necrosis and haemorrhage but the bulk of it shows a whorled structure; on the reverse of the specimen a separate small nodule of tumour can be seen.
At the age of 51, this woman had a leiomyosarcoma excised from the sigmoid colon. Five years later she presented with a three-day history of abdominal pain and on examination an abdominal mass was noted. Death occurred during this admission from massive pulmonary embolism. The histology of the lesion seen here is that of a leiomyosarcoma.