GALLBLADDER - Chronic cholecystitis & stones

The gallbladder is markedly and irregularly thickened; the mucosa shows extensive ulceration and there is calculus material in the wall at several points. The outer surface of the gallbladder shows adhesion by omental fat and one area where the liver is firmly adherent to the bladder. Mounted with the specimen are the stones which were present.
This woman presented at the age of 71 with indigestion; she complained of a dull persistent ache at the lower end of the sternum radiating around both sides. There was tenderness in the right upper quadrant of the abdomen and a nodular mass was palpable.