LIVER - Hodgkins Disease

The specimen consists of a slice of liver sectioned in the horizontal plane. The lobular architecture of the liver is accentuated macroscopically by the presence of multiple tumour nodules. These appear to have a predominantly perivascular distribution and are also well seen in the immediate subcapsular region. Histologically this diffuse infiltrate was found to be Hodgkins disease.
This 70-year-old man presented with a short history of night sweats and weight loss. An enlarged cervical lymph node was noted clinically. This was biopsied and showed lymphocyte depleted Hodgkins disease. This was staged at IVB. The patient was started on cytotoxic therapy, however progressive deterioration in his mental and physical state occurred and he died of bronchopneumonia two weeks after admission.