LIVER - Cirrhosis and hepatocellular carcinoma

The specimen is a slice of liver tissue. The right lobe shows a predominantly micronodular cirrhosis, although occasional large hepatic nodules are seen. The left lobe of the liver has been almost totally replaced by a large nodular tumour mass, this shows microcystic degeneration with foci of necrosis and haemorrhage. The tumour has the histological appearances of a hepatocellular carcinoma.
The patient, a 52 year old woman, was admitted with vague abdominal symptoms and died suddenly. The cirrhosis and hepatocellular carcinoma were discovered at postmortem. There were no known predisposing factors.