PROSTATE - Carcinoma

This shows prostate and a portion of bladder. The prostate is greatly, but almost symmetrically, enlarged, and shows a prominent middle lobe; posteriorly, one can see tumour tissue extending into the paravesicle areas. The cut surface of the prostate is vaguely nodular, but shows none of the characteristic nodules of benign hyperplasia.
This man was admitted to hospital approximately a fortnight before death, with an established diagnosis of carcinoma of the prostate, and showing increased urinary difficulty. Investigation showed bony deposits; the histology of the tumour was that of a well-differentiated adenocarcinoma of the prostate. The regional lymph nodes were involved, as was the vertebral column.