URETER - Metastatic carcinoma

The specimens are those of a hemisected kidney and portion of ureter. The mucosal surface of the ureter appears normal. The distal portion contains a partially encircling tumour mass. This is pale and has a nodular consistency. The kidney shows a moderate degree of hydronephrosis with dilatation of the renal pelvis and major calyces. There is early nephrosclerosis with blurring of the normal cortico-medullary demarcation. A small simple cortical cyst is seen on the surface of the kidney.
This elderly man was known to have adenocarcinoma of the prostate in addition to metastatic malignant melanoma. At postmortem examination it was found that the prostatic carcinoma had extended into the base of the bladder and up both ureters, causing bilateral hydronephrosis.