THYROID - Nodular goitre

Viewed from the front of the jar, one can see that the thyroid is extensively enlarged by numerous nodules, measuring up to 4 cm. in diameter; some of these nodules show degenerative changes, while other appear to consist entirely of colloid. The reverse side of the specimen shows more clearly the extent of the lesions, with considerable enlargement of both lobes, and involvement of the isthmus. The lower pole of the right lobe extends downwards for some centimetres.
This young woman presented at the age of 22 years with a history of gradual enlargement of a goitre, recently causing difficulty with breathing and swallowing. At operation, nodules were found extending behind the oesophagus on the right side below the clavicle. The histology of the lesion was that of a simple nodular goitre.